87657-69-0Relevant academic research and scientific papers
Synthesis of diarylheptanoids and assessment of their pungency
Itokawa,Aiyama,Ikuta
, p. 2491 - 2496 (2007/10/02)
With the aim of correlating pungency with substituent groups on one benzene ring, various analogues of yakuchinones were synthesized by means of the Claisen-Schmidt reaction. Their pungencies were assessed by direct comparison of the threshold concentrations obtained in taste experiments. The presence of a phenolic hydroxyl group was indispensable for high pungency, while that of a 1,2-double bond of the heptanone part tended to decrease the pungency.
