876589-83-2

Upstream product

• 876589-82-1 tert-butyl ((1r,4r)-4-((2-nitrophenyl)amino)cyclohexyl)carbamate 
• 2615-25-0 trans-1,4-cyclohexyldiamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 177906-48-8 trans-N-Boc-1,4-cyclohexanediamine 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 876589-87-6 1,1-dimethylethyl {trans-4-[(2-{[N-methyl-N-(5,6,7,8-tetrahydro-8-quinolinyl)glycyl]amino}phenyl)amino]cyclohexyl}carbamate 
• 1456506-59-4 tert-butyl ((1r,4r)-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)carbamate 
• 1456507-11-1 1-((1r,4r)-4-((2-hydroxy-2-phenylpropyl)amino)cyclohexyl)-1H-benzo[d]imidazol-2(3H)-one 
• 1456505-02-4 (R+S) 5-methyl-3-((1r,4r)-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)-5-phenyloxazolidin-2-one 
• 1456506-58-3 1-((1r,4r)-4-aminocyclohexyl)-1H-benzo[d]imidazol-2(3H)-one hydrochloride 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME

A heterocyclic compound represented by formula XI, a pharmaceutically acceptable salt, a solvate, or a solvate of a pharmaceutically acceptable salt thereof, use thereof, and a composition containing the same. The compound is novel in structure and has good STAT5 inhibitory activity.

OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF

Compounds of Formula (I) and Formula (II) are useful inhibitors of tankyrase. Compounds of Formula (I) and Formula (II) have the following structure: where the definitions of the variables are provided herein.

CHEMICAL COMPOUNDS

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.