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(8S)-N-methyl-N-{(1S)-1-[4-(methyloxy)phenyl]ethyl}-5,6,7,8-tetrahydro-8-quinolinamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

876590-09-9

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876590-09-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 876590-09-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,6,5,9 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 876590-09:
(8*8)+(7*7)+(6*6)+(5*5)+(4*9)+(3*0)+(2*0)+(1*9)=219
219 % 10 = 9
So 876590-09-9 is a valid CAS Registry Number.

876590-09-9Downstream Products

876590-09-9Relevant articles and documents

Kilogram-scale synthesis of the CXCR4 antagonist GSK812397

Boggs, Sharon,Elitzin, Vassil I.,Gudmundsson, Kristjan,Martin, Michael T.,Sharp, Matthew J.

, p. 781 - 785 (2009)

An improved, scalable synthesis of the CXCR4 antagonist GSK812397 is described. This new route was recently scaled up in 50 L fixed equipment to afford 1.2 kg of drug substance in five steps with an overall yield of 20% and >99% chemical and enantiomeric

Amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines as CXCR4 antagonists with potent activity against HIV-1

Gudmundsson, Kristjan S.,Sebahar, Paul R.,Richardson, Leah D'Aurora,Miller, John F.,Turner, Elizabeth M.,Catalano, John G.,Spaltenstein, Andrew,Lawrence, Wendell,Thomson, Michael,Jenkinson, Stephen

scheme or table, p. 5048 - 5052 (2010/03/24)

Several novel amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines were synthesized which had potent activity against HIV-1. The synthetic approaches adopted allowed for variation of the substitution pattern and resulting ch

CHEMICAL COMPOUNDS

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Page/Page column 34, (2010/11/28)

The present invention provides compounds of formula (I) including salts, solvates, and pharmaceutically acceptable derivatives thereof, pharmaceutical formulations containing them, processes for their preparation, and methods of treatment using them.

CHEMICAL COMPOUNDS

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Page/Page column 117, (2010/10/20)

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.

CHEMICAL COMPOUNDS

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Page/Page column 164-165, (2010/10/20)

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.

CHEMICAL COMPOUNDS

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Page/Page column 72, (2010/11/08)

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a recep

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