876610-92-3Relevant academic research and scientific papers
A stereoselective oxy-Michael approach to THP*-protected β-hydroxy esters
Hernandez-Juan, Felix A.,Xiong, Xin,Brewer, Sarah E.,Buchanan, David J.,Dixon, Darren J.
, p. 3283 - 3286 (2005)
The 'naked' anion of (S)-6-methyl δ-lactol undergoes efficient oxy-Michael addition to α,β-unsaturated methyl sulfones to give the corresponding adducts with excellent (up to 99% de) stereocontrol at the newly formed stereogenic β-centre. The successive r
