87665-53-0Relevant academic research and scientific papers
Synthetic and structural studies on 1,2,4-dithiazolidine-3,5-dione derivatives
Wood, Mark E.,Cane-Honeysett, Daniel J.,Dowle, Michael D.,Coles, Simon J.,Hursthouse, Michael B.
, p. 3015 - 3023 (2003)
Methods have been developed for the N-alkylation of 1,2,4-dithiazolidine-3,5-dione 2 and the subsequent conversion of the N-alkylated derivatives into isocyanates 5. An extension of this methodology onto a solid-support is also reported. X-ray crystallographic analysis has been carried out on potassium 1,2,4-dithiazolidine-3,5-dione 3 for structural comparison with the parent heterocycle 2.
1,2,4-Dithiazolidine-3,5-dione: A nucleophilic isocyanate 'building block'
Cane-Honeysett,Dowle,Wood
, p. 1622 - 1624 (2007/10/03)
Mild conditions are described for the direct N-alkylation of 1,2,4-dithiazolidine-3,5-dione 1 using a variety of alkyl halides with subsequent conversion of the products 2 into alkyl isocyanates using triphenylphosphine.
