87671-31-6Relevant academic research and scientific papers
Biosynthesis of the Meroterpenoid Metabolite, Andibenin B: Aromatic Precursors
Bartlett, Alan J.,Holker, John S. E.,O'Brien, Eugene,Simpson, Thomas J.
, p. 1198 - 1200 (1981)
14C- and 2H-Labelling experiments, together with 2H n.m.r. spectroscopy show that ethyl 2,4-dihydroxy-3,5,6-trimethylbenzoate (4) and ethyl 4-hydroxy-2,3,5-trimethylbenzoate (5), but not ethyl 2,4-dihydroxy-6-methylbenzoate (2) or ethyl 4-hydroxy-2-methyl
Synthesis and Regiospecific Deoxygenation of β-Resorcylic Ester Derivatives to 4-Hydroxybenzoates
Bartlett, Alan J.,Holker, John S.E.,O'Brien, Eugene
, p. 667 - 670 (2007/10/02)
Ethyl -4-hydroxy-2-methyl- (6a), and -2,3,5-trimethyl-benzoate (6b), together with ethyl 4-hydroxy-2,3-dimethylbenzoate (6c), have been prepared in satisfactory yields by deoxygenation of the corresponding resorcylate esters, (5a-c), respectively, via hydrogenolysis of their 4-benzyloxy-2-(1-phenyl-1H-tetrazolyloxy)-derivatives, (8a-c).Ethyl 2,4-dihydroxy-5,6-dimethyl-3-trideuterio-methylbenzoate (5d) has been synthesised by trideuteriomethylation of ethyl 2,3-dimethyl-4,6-dioxocyclohexanecarboxylate (10c), followed by dehydrogenation.Preparation of the requisite resorcylate derivatives are included.
