87685-15-2

Basic information

• Product Name: 3-Thiophenamine, 2,4-dimethyl-
• Synonyms: 3-Thiophenamine, 2,4-dimethyl-;2,4-Dimethyl-3-aminothiophene;3-Amino-2,4-dimethylthiophene;2,4-dimethylthiophen-3-amine
• CAS NO: 87685-15-2
• Molecular Formula: C₆H₉NS
• Molecular Weight: 127
• Mol File: 87685-15-2.mol

Chemical Properties

• Boiling Point: 251.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.118±0.06 g/cm3(Predicted)
• PKA: 3.97±0.10(Predicted)
• CAS DataBase Reference: 3-Thiophenamine, 2,4-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenamine, 2,4-dimethyl-(87685-15-2)
• EPA Substance Registry System: 3-Thiophenamine, 2,4-dimethyl-(87685-15-2)

Safety Data

• Hazardous Substances Data: 87685-15-2(Hazardous Substances Data)

Upstream product

• 85006-31-1 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester 
• 106014-16-8 2,5-dimethyl-3-thia-adipic acid 

Downstream Products

• 87676-07-1 N-[(Methoxymethyl)ethyl]-2,4-dimethyl-thiophene-3-amine 
• 87674-68-8 dimethenamid 

Relevant articles and documents

SULFONYLUREA DERIVATIVES AND USES THEREOF

The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.

Method for preparing 3 - amino -2, 4 -dimethylthiophene (by machine translation)

The invention relates to the field, and relates to the field of chloroacetamide preparation. The invention discloses a preparation method, namely 3 -) and -2 dimethylamino 4 - and the method comprises the following steps, 1) cyclization decarboxylation 2, 5 -dimethyl -3 -thiobenzoic acid, 2, 4 -dimethyl tetrahydrothiophene -3 - ketone; 2) rearrangement to obtain 2 amino 4 -3 -dimethylthiophene after condensation with hydroxylamine or a salt thereof in the presence of an acid 3 - anhydride -2 and 4 - a base in the presence of an acid anhydride and a base. By the method, the yield is high, and the yield is high. The preparation method of-amino,dimethylthiophene is suitable for large-scale production. 3 -2 4 . (by machine translation)

Thiophene derivatives of the new solid form and its preparation method and use thereof

The invention relates to thiophene derivatives of the new solid form and its preparation method and use, the thiophene derivatives of the new solid state forms is compound 1 crystalline form I, compound 1 crystalline form II, compound 2 crystalline form I, compound 2 crystalline form II, the invention also relates to containing thiophene derivatives of the new solid form pharmaceutical composition and can be used for the local anesthetic and/or analgesic drug in the field of application. The present invention provides powder X - with obvious-ray diffraction Atlas characteristics of the new solid form, its preparation method is simple, it is convenient to store, is suitable for preparing a plurality of preparations,

Heterocyclic acylamide derivative and preparation method and pharmaceutical application thereof

The invention relates to a heterocyclic acylamide derivative and a preparation method and pharmaceutical application thereof, in particular to a heterocyclic acylamide derivative shown as a general formula (I) or a stereoisomer and a pharmaceutically-acce

Herbicidal N-thienyl-chloroacetamides

The invention provides 5-membered heteroaromatic compounds of formula I wherein Ar is a 5-membered heteroaromatic group comprising 1 or 2 heteroatoms selected from O, S and N and linked by a ring C-atom to the N-atom of the N(Y)COCH2 Cl group to which it is bound, whereby where Ar is pyrazolyl, said N(Y)COCH2 Cl group is in the 4-position, and Y is as specified in the description, the use of these compounds as herbicides, compositions for facilitating such use and the preparation of the chloroacetamides.

Thiophene derivatives

The invention provides novel N-acylamino thiophene derivatives, e.g. N-(methoxyacetyl)-N-(5-bromo-4-methyl-2-methylthiothien-3-yl)alanine methyl ester, which are useful as fungicides. Other objects of the invention are fungicidal compositions comprising such novel compounds and methods of combatting phytopathogenic fungi with the acid of said novel compounds.