876912-74-2Relevant academic research and scientific papers
Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists
Evindar, Ghotas,Satz, Alexander L.,Bernier, Sylvie G.,Kavarana, Malcolm J.,Doyle, Elisabeth,Lorusso, Jeanine,Taghizadeh, Nazbeh,Halley, Keith,Hutchings, Amy,Kelley, Michael S.,Wright, Albion D.,Saha, Ashis K.,Hannig, Gerhard,Morgan, Barry A.,Westlin, William F.
scheme or table, p. 2315 - 2319 (2009/12/07)
In pursuit of potent and selective sphingosine-1-phosphate receptor agonists, we have utilized previously reported phenylamide and phenylimidazole scaffolds to explore extensive side-chain modifications to generate new molecular entities. A number of desi
