876938-69-1

Upstream product

• 78-77-3 Isobutyl bromide 
• 7693-52-9 4-bromo-2-nitrophenol 

Downstream Products

• 1415309-96-4 C₁₆H₂₄BNO₅ 
• 144060-92-4 ethyl 2-[3-amino-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylate 
• 144060-93-5 ethyl 4-methyl-2-[3-nitro-4-(2-methylpropoxy)phenyl]-1,3-thiazole-5-carboxylate 

Relevant academic research and scientific papers

AZOLE BENZENE DERIVATIVE AND CRYSTALLINE FORM THEREOF

There are provided: 4-methyl-2-[4-(2-methylpropoxy)-3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-1,3-thiazole-5-carboxylic acid, a sodium salt thereof and crystals of these, useful as a therapeutic agent and a prophylactic agent for gout, hyperuricemia and the like, and a method for producing the same.

2-PHENYLTHIOPHENE DERIVATIVE

The present invention relates to a 2-phenylthiophene derivative or a salt thereof, wherein the thiophene ring is substituted with a carboxyl group or the like and the benzene ring has an electron-withdrawing group such as a cyano group and an electron-donating group such as a substituted alkoxy group at the same time. Since the compound of the invention has good xanthine oxidase-inhibitory action and uric acid-lowering action and does not have a structure derived from nucleic acid, the compound has advantages of high safety and excellent effects as compared with conventional compounds and is useful as a therapeutic or preventive agent for hyperuricemia, gout, inflammatory bowel diseases, diabetic kidney diseases, diabetic retinopathy, or the like.