876954-53-9

Upstream product

• 1033230-97-5 4(R)-acryloxy-6-benzyloxy-3(S),5(S)-dimethyl-1-hexene 
• 876954-51-7 (S)-N-[(2R,3S,4S)-5-benzyloxy-3-tert-butyldimethylsilyloxy-2,4-dimethylpentanoyl]-4-isopropyl-1,3-thiazolidine-2-thione 
• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 444109-42-6 (2S,3R,4S)-5-benzyloxy-3-(tert-butyldimethylsilyloxy)-2,4-dimethyl-pentanal 

Downstream Products

• 876954-56-2 (5S,6R)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-5-methyl-5,6-dihydro-2H-pyran-2-ol 
• 876954-54-0 (R)-2-[(2R,5S,6R)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-5-methyl-5,6-dihydro-2H-pyran-2-yl]-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-butan-1-one 
• 876954-46-0 (R)-methyl 2-[(2R,5S,6R)-6-[(S)-1-benzyloxypropan-2-yl]-5-methyl-5,6-dihydro-2H-pyran-2-yl]butanoate 
• 876954-50-6 (2R,3S)-2-[(S)-1-benzyloxypropan-2-yl]-6-methoxy-3-methyl-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Synthetic studies toward C3-C9 segment of Soraphen A1α

The ring-closure metathesis of the diene (2S,3R,4S)-1-(tert- butyldiphenylsilyloxy)-2,4-dimethylhex-5-en-3-yl acrylate produced the dihydropyrone with the correct stereochemistry for Soraphen A1α synthesis. The C2,C3 stereocenters were introduced by the a

Stereoselective synthesis of the western hemisphere of salinomycin

A convergent and module-based strategy for the asymmetric synthesis of the western hemisphere (C1-C17 fragment) of salinomycin has been devised. This new synthetic approach relies on highly stereoselective C-glycosidation and aldol processes.