87707-11-7Relevant academic research and scientific papers
Mechanism of C-F reductive elimination from palladium(IV) fluorides
Furuya, Takeru,Benitez, Diego,Tkatchouk, Ekaterina,Strom, Alexandra E.,Tang, Pingping,Goddard III, William A.,Ritter, Tobias
supporting information; experimental part, p. 3793 - 3807 (2010/05/15)
The first systematic mechanism study of C-F reductive elimination from a transition metal complex is described. C-F bond formation from three different Pd(IV) fluoride complexes was mechanistically evaluated. The experimental data suggest that reductive elimination occurs from cationic Pd(IV) fluoride complexes via a dissociative mechanism. The ancillary pyridyl-sulfonamide ligand plays a crucial role for C-F reductive elimination, likely due to a K 3 coordination mode, in which an oxygen atom of the sulfonyl group coordinates to Pd. The pyridyl-sulfonamide can support Pd(IV) and has the appropriate geometry and electronic structure to induce reductive elimination.
Studies into the generation and Diels-Alder reactions of 7,8-quinolyne with furan dienes
Collis, Gavin E.,Burrell, Anthony K.
, p. 3653 - 3656 (2007/10/03)
Reaction of an appropriate ortho-halo tosylate precursor with organolithium reagents provides the first conclusive route to the intermediate, 7,8-quinolyne. The transient existence of this hetaryne was confirmed by Diels-Alder reactions with furan derivatives that provide endoxide adducts. Chemical induced rearrangement of these adducts allows entry to key compounds of 10-hydroxy[h]benzoquinoline and its 7-substituted derivatives in modest yields.
