87708-06-3Relevant academic research and scientific papers
Derives de l'isocyanate de chlorosulfonyle. Synthese, structure et activite biologique d'halogeno-2 ethoxycarbonylsulfamides
Agoh, Bernadette,Dewynter, Georges,Montero, Jean-Louis,Leydet, Alain,Imbach, Jean-Louis
, p. 867 - 872 (2007/10/02)
New 2-chloroethoxycarbonylsulfamides are synthesized in a two step reaction from C.S.I., haloethanol and various primary and secondary amines.Cyclization of these sulfamides in basic medium gives the corresponding sulfamyl-oxazolidinones.All structures are established by IR, NMR, MS and RX diffraction data.The antitumor activity of the products towards LI210 is reported.
SELECTIVE SYNTHESIS OF SULFONYLUREAS AND CARBOXYSULFAMIDES. A NOVEL ROUTE TO OXAZOLIDINES.
Montero, Jean-Louis,Dewynter, Georges,Agoh, Bernadette,Delaunay, Barbara,Imbach, Jean-Louis
, p. 3091 - 3094 (2007/10/02)
Starting with chlorosulfonylisocyanate (CSI) two new series of 2-haloethyl carboxysulfamides 5 and 2-haloethyl oxosulfonylureas 6 have been prepared.The haloethyl carboxylate 5 underwent a novel cyclisation in the presence of Et3N to furnish quantitative
