87708-32-5

Upstream product

• 75507-26-5 2-(hydroxymethyl)-12-crown-4 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1373434-01-5 benzyl 4-((1,4,7,10-tetraoxacyciododecan-2-yl)methylthio)-2-methylbutan-2-ylcarbamate 
• 109953-99-3 [5-Decyl-2-(1,4,7,10-tetraoxa-cyclododec-2-ylmethoxy)-phenyl]-phosphonic acid monoethyl ester 
• 126128-17-4 [5-Decyl-2-(1,4,7,10-tetraoxa-cyclododec-2-ylmethoxy)-phenyl]-phosphonic acid 
• 144381-58-8 [5-Decyl-2-(1,4,7,10-tetraoxa-cyclododec-2-ylmethoxy)-phenyl]-phosphonic acid diethyl ester 
• 87708-35-8 5-Decyl-2-(1,4,7,10-tetraoxa-cyclododec-2-ylmethoxy)-benzoic acid methyl ester 
• 87708-27-8 5-Decyl-2-(1,4,7,10-tetraoxa-cyclododec-2-ylmethoxy)-benzoic acid 

Relevant academic research and scientific papers

Sulfoxides as response elements for fluorescent chemosensors

Sulfoxides are shown to be viable reporting groups for fluorescent chemosensor development. Metal coordination of sulfoxide-appended fluorophores suppresses excited-state pyramidal inversion of the sulfoxide, leading to enhanced fluorescence emission. This new structural motif allows the construction of fluorescent chemosensors that do not require nitrogen coordination as part of the signaling process, that have a range of selectivities and affinities for oxophilic metal ions, and that can function in water.

Platinum(II) complexes, their preparation and use as anti-tumor agents

Compounds of formula I STR1 wherein R1 and R2, that can be the same or different, are hydrogen, alkyl, aryl, aralkyl groups or, if taken together, cycloalkyl groups; A is a carbon atom, a residue of 2,3-dioxybutandioic-2,4-dioxyphtalic acid or disubstituted malonic acid derivatives; n1 and n2 are selected in such a manner that the result of their addition is from 2 to 40; T1 and T2 that can be the same or different, are hydrogen, alkyl, benzyl, phenyl, acyl or cycloalkyl or a residue of formulae STR2 Compounds I are useful as anti-tumor agents in human therapy.

NOVEL LIPOPHILIC CROWN CARBOXYLIC ACIDS

Four novel ionizable crowns are formed from reactions of methyl 5-(n-decyl)salicylate with tosylates from hydroxymethyl-12-crown-4, -15-crown-5, -18-crown-6 and -21-crown-7 followed by hydrolysis.