877080-71-2Relevant academic research and scientific papers
An efficient synthesis of difluoropropargyl bromides
Xu, Bo,Mae, Masayuki,Hong, Jiyoung A.,Li, Youhua,Hammond, Gerald B.
, p. 803 - 806 (2007/10/03)
High yields of γ-alkyl, -silyl and -aryl-substituted difluoropropargyl bromides have been obtained by monitoring concentration and temperature in the reaction between CF2Br2 and γ-substituted lithium acetylide. γ-Silyl substituents afforded the corresponding α,α,α-difluorobromopropargyl alcohols in good yields via cleavage of tetrabutylammonium fluoride in the presence of an aldehyde. Georg Thieme Verlag Stuttgart.
