877082-48-9Relevant academic research and scientific papers
Efficient synthesis of N-protected 1-substituted homotaurines from a xanthate and olefins
Huang, Zhongyan,Xu, Jiaxi
, p. 1050 - 1056 (2013/02/23)
A series of N-protected 1-substituted homotaurines was synthesized efficiently from various olefins with O-ethyl S-2-phthalimidomethylxanthate as a sulfur-aminomethylation reagent via a radical addition and subsequent performic acid oxidation. The current method is a convenient and practical method for the synthesis of 1-substituted homotaurines with high yields and short synthetic route.
Bismuth triflate-catalyzed addition of allylsilanes to N- alkoxycarbonylamino sulfones: Convenient access to 3-Cbz-protected cyclohexenylamines
Ollevier, Thierry,Li, Zhiya
supporting information; experimental part, p. 3251 - 3259 (2010/04/24)
Bismuth triflate was found to be an efficient catalyst in the Sakurai reaction of allyltrimethylsilanes with N-alkoxycarbonylamino sulfones. The reaction proceeded smoothly with a low catalyst loading of Bi(OTf) 3·4H2O (2-5 mol%) to afford the corresponding protected homoallylic amines in very good yields (up to 96%). A sequential allylation reaction followed by ring-closing metathesis delivers 6-8 membered 3-Cbz-protected cycloalkenylamines.
S-(3-Chloro-2-oxo-propyl)-O-ethyl xanthate: A linchpin radical coupling agent for the synthesis of heterocyclic and polycyclic compounds
Bergeot, Olga,Corsi, Camilla,El Qacemi, Myriem,Zard, Samir Z.
, p. 278 - 290 (2007/10/03)
The preparation and use of S-(3-chloro-2-oxo-propyl)-O-ethyl xanthate to directly introduce an α-chloroketone motif is described, along with applications for the synthesis of heterocyclic and polycyclic structures. The Royal Society of Chemistry 2006.
