877145-02-3

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]-
• CAS NO: 877145-02-3
• Molecular Formula: C20H19Cl2N3O2
• Molecular Weight: 404.296
• Mol File: 877145-02-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]-(877145-02-3)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]-(877145-02-3)

Safety Data

• Hazardous Substances Data: 877145-02-3(Hazardous Substances Data)

Upstream product

• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 41202-77-1 1-(2,3-dichlorophenyl)piperazine 
• 119532-26-2 1-(2,3-dichlorophenyl)-piperazine hydrochloride 

Downstream Products

• 744209-03-8 {2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine 
• 744209-04-9 {2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine 
• 163620-93-7 2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethanamine 

Relevant articles and documents

ARYLPIPERAZINE-CONTAINING PURINE DERIVATIVES AND USES THEREOF

A novel arylpiperazine-containing purine derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating depressive disorders, are provided.

ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS

The present invention relates to novel arylpiperazine-containing pyrrole 3-carboxamide derivatives of formula (I) or a pharmaceutically acceptable salt thereof which is useful for preventing or treating depressive disorders. The present invention also provides a method for preparing the arylpiperazine-containing pyrrole 3-carboxamide derivatives or the pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and a method for preventing or treating depressive disorders.

Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT2A, 5-HT2C, and the serotonin transporter as a potential antidepressant

Arylpiperzine-containing pyrrole 3-carboxamide derivatives were synthesized and evaluated as novel antidepressant compounds. The various analogues were efficiently prepared and bio-assayed for binding to 5-HT2A, 5-HT2C receptor, and