87730-93-6Relevant academic research and scientific papers
140. Construction of Highly Substituted Nitroaromatic Systems by Cyclocondensation. Part I. Synthesis of 4-Nitro-3-oxobutyrate
Duthaler, Rudolf O.
, p. 1475 - 1492 (2007/10/02)
Methyl 4-nitro-3-oxobutyrate (1) is prepared by substitution of 4-bromo- and 4-iodo-3-oxobutyrate enol ether or enol acetate derivatives with nitrite and deprotection of the keto function (Schemes 2 and 3).A much more convenient access to 1 is, however, t
