87731-05-3Relevant academic research and scientific papers
Conformationally defined adrenergic agents. 1. Design and synthesis of novel α2 selective adrenergic agents: Electrostatic repulsion based conformational prototypes
DeBernardis,Kerkman,Winn,Bush,Arendsen,McClellan,Kyncl,Basha
, p. 1398 - 1404 (2007/10/02)
A previous report of the adrenergic selectivity of 2- and 6-fluoronorepinephrine prompted us to formulate a hypothesis that accounted for this selectivity on the basis of a conformational preference induced by electrostatic repulsion between the aromatic
