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2-AMINO-1-(4-METHOXY-3-NITRO-PHENYL)-ETHANONE HYDROCHLORIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

877395-19-2

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877395-19-2 Usage

Preparation

Obtained by treatment of a-bromo-4-methoxy-3nitro-acetophenone with hexamethylenetetramine in chloroform at r.t. for 1 h.

Check Digit Verification of cas no

The CAS Registry Mumber 877395-19-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,7,3,9 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 877395-19:
(8*8)+(7*7)+(6*7)+(5*3)+(4*9)+(3*5)+(2*1)+(1*9)=232
232 % 10 = 2
So 877395-19-2 is a valid CAS Registry Number.

877395-19-2Relevant academic research and scientific papers

Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents

Xue, Na,Yang, Xiaochun,Wu, Rui,Chen, Jing,He, Qiaojun,Yang, Bo,Lu, Xiuyang,Hu, Yongzhou

, p. 2550 - 2557 (2008/09/21)

A new series of aryl substituted imidazol-2-one derivatives structurally related to combretastatin A-4 (CA-4) were synthesized and evaluated for their cytotoxic activities in vitro against various human cancer cell lines including MDR cell line. The cytotoxic effects of compounds 7b and 7i proved to be similar to or greater than that of docetaxel. The highly active compound 7b also exhibited excellent inhibitory activity on tumor growth in vivo.

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