877400-35-6

Upstream product

• 877400-09-4 [(R)-1-Hydroxy-3-(2-triisopropylsilanyloxy-ethyl)-indan-1-yl]-acetic acid ethyl ester 
• 877400-12-9 [(1R,3S)-3-(2-Triisopropylsilanyloxy-ethyl)-indan-1-yl]-acetic acid ethyl ester 
• 877400-11-8 [(S)-3-(2-Triisopropylsilanyloxy-ethyl)-indan-(1E)-ylidene]-acetic acid ethyl ester 
• 877400-15-2 2-[(1R,3S)-3-(2-Triisopropylsilanyloxy-ethyl)-indan-1-yl]-acetamide 
• 877400-14-1 [(1R,3S)-3-(2-Triisopropylsilanyloxy-ethyl)-indan-1-yl]-acetic acid 
• 877400-07-2 (R)-3-(2-Triisopropylsilanyloxy-ethyl)-indan-1-one 
• 877400-17-4 2-[(1R,3S)-3-(2-Hydroxy-ethyl)-indan-1-yl]-acetamide 
• 877400-19-6 2-[(1R,3S)-3-(2-Oxo-ethyl)-indan-1-yl]-acetamide 
• 877400-05-0 (R)-3-(2-Hydroxy-ethyl)-indan-1-one 
• 877400-03-8 ((R)-3-Oxo-indan-1-yl)-acetaldehyde 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2′ side chains

A series of monopyrrolinone-based HIV-1 protease inhibitors possessing rationally designed P2′ side chains have been synthesized and evaluated for activity against wild-type HIV-1 protease. The most potent inhibitor displays subnanomolar potency in vitro