87742-49-2Relevant academic research and scientific papers
A useful method for preparation of carboxylic acids from terminal alkynes
Abrams, Suzanne R.
, p. 2423 - 2424 (2007/10/02)
Substituted acetic acids can be prepared in good yield (50-80percent) from terminal acetylenes of the same chain length.The alkyne is first converted to the thiophenyl ether, which is treated without purification with mercuric sulfate in acetic acid and 2N sulfuric acid affording the carboxylic acid.The method is particularly useful in the synthesis of long chain ω-hydroxyalkanoic acids.
