877457-66-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Methoxyquinoxaline-5-carbaldehyde is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the structure of various biologically active compounds. Its presence in the molecular structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
3-Methoxyquinoxaline-5-carbaldehyde is used as a building block in the development of agrochemicals, such as pesticides and herbicides, due to its reactivity and potential to form biologically active molecules. This contributes to the creation of more effective and targeted agricultural products.
Used in Medicinal Chemistry:
3-Methoxyquinoxaline-5-carbaldehyde is utilized as a valuable component in medicinal chemistry for its potential to contribute to the discovery and development of new drugs. Its unique structure allows for the exploration of various chemical reactions and the synthesis of novel compounds with potential therapeutic properties.
Used in Drug Discovery:
3-Methoxyquinoxaline-5-carbaldehyde plays a significant role in drug discovery as a versatile intermediate that can be used to create a wide range of heterocyclic compounds. Its presence in these compounds can lead to the identification of new drug candidates with improved efficacy and selectivity in treating various diseases and conditions.

Upstream product

• 877457-65-3 8-(dibromomethyl)-2-methoxyquinoxaline 
• 61148-20-7 2-cyano-N-(2-methyl-6-nitrophenyl)acetamide 
• 61148-21-8 2-cyano-3-hydroxy-5-methylquinoxaline 1-oxide 
• 61148-22-9 8-methyl-2-hydroxyquinoxaline 
• 61148-40-1 2-chloro-8-methylquinoxaline 
• 570-24-1 2-Methyl-6-nitroaniline 
• 877457-64-2 2-methoxy-8-methyl-quinoxaline 

Downstream Products

• 1163127-96-5 (3-methoxy-quinoxalin-5-ylmethyl)-triphenyl-phosphonium bromide 

Relevant academic research and scientific papers

Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity

There is an urgent need for new antibacterial drugs that are effective against infections caused by multidrug-resistant pathogens. Novel nonfluoroquinolone inhibitors of bacterial type II topoisomerases (DNA gyrase and topoisomerase IV) have the potential

4-(1-AMINO-ETHYL)-CYCLOHEXYLAMINE DERIVATIVES

The invention relates to compounds of formula (I) wherein R0 represents H or OH; R1 represents alkoxy; U and W represent N, V represents CH and R2 represents H or F, or U and V represent CH, W represents N and R2 /su

CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic cyclohexyl or piperidinyl carboximide derivatives of formula (I) wherein R1 represents hydrogen, halogen, (C1-C4)alkyl, (C1-C4)alkoxy, cyano or COOR2, R2 being (C1-C4)alkyl;one or two of U, V, W and X represent(s) N and the remaining represent each CH, or, in the case of X, may also represent CRX, RX being a halogen atom;either B represents N and A represents CH2CH2 or CH(OR3)CH2, or B represents CH or C(OR4) and A represents OCH2, CH2CH(OR5), CH(OR6)CH2, CH(OR7)CH(OR8), CH═CH or CH2CH2;each of R3, R4, R5, R6, R7, and R8 represents independently hydrogen, SO3H, PO3H2, CH2OPO3H2 or COR9, R9 being either CH2CH2COOH or such that R9—COOH is naturally occurring amino acid or dimethylaminoglycine;and to salts of such compounds of formula (I).

ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic ethanol or 1,2-ethanediol cyclohexyl derivatives of formula (I) wherein R1 represents (C1-C4)alkoxy; one or two of U, V, W and X represent(s) N and the remaining represent each independently CH or, in the case of V or X

CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic cyclohexyl or piperidinyl carboxamide derivatives of formula (I) wherein R1 represents hydrogen, halogen, (C1-C4)alkyl, (C1-C4)alkoxy, cyano or COOR2, R2 being (C1-C4)alkyl; one or two of U, V, W and X represent(s) N and the remaining represent each CH, or, in the case of X, may also represent CRx, Rx being a halogen atom; either B represents N and A represents CH2CH2 or CH(OR3)CH2, or B represents CH or C(OR4) and A represents OCH2, CH2CH(OR5), CH(OR6)CH2, CH(OR7)CH(OR8), CH=CH or CH2CH2; each of R3, R4, R5, R6, R7 and R8 represents independently hydrogen, SO3H, PO3H2, CH2OPO3H2 or COR9, R9 being either CH2CH2COOH or such that R9-COOH is a naturally occurring amino acid or dimethylaminoglycine; and to salts of such compounds of formula (I).

New Piperidine Antibiotics

The invention relates to novel, antibacterially active piperidine derivatives of the formula wherein one of U and V represents N, the other represents N or CH; M represents CH2CH2, CH═CH, CH(OH)CH(OH), CH(OH)CH2, CH(NHsub

ANTIBIOTIC COMPOUNDS

The invention relates to selected antibiotics of formula (Al) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also repr

NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY

The present invention describes novel anti-bacterial compounds of formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase.

NEW PIPERIDINE ANTIBIOTICS

The invention relates to novel, antibacterially active piperidine derivatives of the formula (I) wherein one of U and V represents N, the other represents N or CH; M represents CH2CH2, CH=CH, CH(OH)CH(OH), CH(OH)CH2, CH(NH