877609-94-4Relevant academic research and scientific papers
14-Membered cyclodepsipeptides with alternating β-hydroxy and α-amino acids by cyclodimerization
Iliev, Boyan,Linden, Anthony,Kunz, Roland,Heimgartner, Heinz
, p. 1079 - 1094 (2007/10/03)
The cyclodimerization (twinning) of β-hydroxy acid amides of type 1 under 'direct amide cyclization' (DAC) conditions is described. Although other coupling methods also gave moderate results, best yields were obtained via DAC, reaching 88% for the cyclodi
