877619-67-5

Basic information

• Product Name: 4-(6-amino-5-benzyloxy-pyridin-3-yl)-benzoic acid
• Synonyms: 4-(6-amino-5-benzyloxy-pyridin-3-yl)-benzoic acid
• CAS NO: 877619-67-5
• Molecular Weight: 320.348
• Mol File: 877619-67-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(6-amino-5-benzyloxy-pyridin-3-yl)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-amino-5-benzyloxy-pyridin-3-yl)-benzoic acid(877619-67-5)
• EPA Substance Registry System: 4-(6-amino-5-benzyloxy-pyridin-3-yl)-benzoic acid(877619-67-5)

Safety Data

• Hazardous Substances Data: 877619-67-5(Hazardous Substances Data)

Upstream product

• 754230-78-9 3-(benzyloxy)-5-bromopyridine-2-amine 
• 180516-87-4 4-carboxyphenylboronic acid pinacol ester 

Downstream Products

• 756520-43-1 (R)-(4-(5-benzyloxy-6-aminopyridin-3-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone 

Relevant articles and documents

AMINOHETEROARYL COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS

Aminoheteroaryl compounds are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.

AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.