877674-82-3 Usage
General Description
The chemical "2-Heptenoic acid, 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl] carbonyl]amino]-, monoammonium salt, (2Z)-" is a complex compound containing a carboxylic acid group, an amino acid group, and a monoammonium salt group. It is also characterized by the presence of a cyclopropyl carbonyl group. The compound is in the Z configuration, meaning that the two highest priority groups on each end of a double bond are on the same side. 2-Heptenoic acid,
7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]
carbonyl]amino]-, monoammonium salt, (2Z)- may have various industrial or pharmaceutical applications, given its complex structure and potential reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 877674-82-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,7,6,7 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 877674-82:
(8*8)+(7*7)+(6*7)+(5*6)+(4*7)+(3*4)+(2*8)+(1*2)=243
243 % 10 = 3
So 877674-82-3 is a valid CAS Registry Number.
877674-82-3Relevant academic research and scientific papers
NOVEL PROCESS FOR THE PREPARATION OF CILASTATIN SODIUM SALT
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Page/Page column 12-13, (2010/10/20)
The present invention relates to a novel process for preparing cilastatin sodium salt used asa dehydropeptidase 1 inhibitor. The novel method of the present invention could prevent the formation of (E)-isomer from the preparation of intermediate for preparing cilastatin sodium, i.e., (Z)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxarnido)-2-heptenoic acid metal salt and isolate the intermediate in situ providing simpler process with high yield and purity. Furthermore, it can provide with highly pure cilastatin sodium salt by isolating novel cilastatin amine salt and using by sodium hydroxide and cationic exchange resin. Accordingly, the method can be very useful in preparing cilastatin sodium salt with high yield and high purity.
