877678-68-7Relevant academic research and scientific papers
The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices
Liu, Feng,Zhang, Guoming,Hornby, Geoffrey,Vasylyev, Dmytro,Bowlby, Mark,Park, Kaapjoo,Gilbert, Adam,Marquis, Karen,Andree, Terrance H.
, p. 262 - 268 (2006)
Positive allosteric modulators of metabotropic glutamate receptor subtype 5 (mGlu5) have promising therapeutic potential. The effects of selective mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices have not been previousl
TRIAZOLOBENZODIAZEPINES AND THEIR USE AS VASOPRESSIN ANTAGONISTS
-
Page/Page column 29, (2010/10/20)
Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein R represents H, C1-6 alkyl, SO2R1, SO2NR1R2, or COR1; R1 and R2 independently represent C1-6alkyl; and Ring A represents a phenyl ring or a pyridinyl ring; may be useful in the treatment of anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhoea (primary and secondary), endometriosis, emesis (including motion sickness), intrauterine growth retardation, inflammation (including rheumatoid arthritis), mittlesmerchz, preclampsia, premature ejaculation, premature (preterm) labor and Raynaud's disease.
