877774-45-3

Upstream product

• 131474-72-1 N²-phenoxyacetyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)guanosine 
• 877774-46-4 N²-phenoxyacetyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-O-(2-cyanoethoxymethyl)guanosine 

Downstream Products

• 863408-43-9 N²-phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-cyanoethoxymethyl)guanosine 

Relevant academic research and scientific papers

METHOD FOR INTRODUCING NUCLEIC-ACID-PROTECTING GROUP

It is an object of the invention to provide a simple and economical method for introducing the following substituent (I) at the 2'-hydroxyl group of the ribose of a ribonucleic acid derivative whose 3'-hydroxyl group and 5'-hydroxyl group are protected wi

METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID

A method is provided for removing a 2-cyanoethoxymethyl (CEM) group and substituting the 2′-hydroxyl group of each ribose of an oligonucleic acid derivative with good reproducibility and high efficiency.

METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP

The main object of the present invention is to provide a method for efficiently removing the silicon substituent which protects the 3'-hydroxyl group and the 5'-hydroxyl group of a ribose of a ribonucleic acid derivative in which the 2'-hydroxyl group of

PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA

An object of the present invention is to provide a useful and novel phosphoramidite compound for the synthesis of oligo-RNA. A phosphoramidite compound represented by the following general formula (1), wherein: Bx represents a nucleobase which