877791-45-2Relevant academic research and scientific papers
Selective activity against Mycobacterium tuberculosis of new quinoxaline 1,4-di-N-oxides
Vicente, Esther,Pérez-Silanes, Silvia,Lima, Lidia M.,Ancizu, Saioa,Burguete, Asunción,Solano, Beatriz,Villar, Raquel,Aldana, Ignacio,Monge, Antonio
experimental part, p. 385 - 389 (2011/03/17)
New series of 3-phenylquinoxaline 1,4-di-N-oxide with selective activity against Mycobacterium tuberculosis have been prepared and evaluated. Thirty-four of the seventy tested compounds showed an MIC value less than 0.2 μg/mL, a value on the order of the
Synthesis and structure-activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents
Vicente, Esther,Lima, Lidia M.,Bongard, Emily,Charnaud, Sarah,Villar, Raquel,Solano, Beatriz,Burguete, Asuncion,Perez-Silanes, Silvia,Aldana, Ignacio,Vivas, Livia,Monge, Antonio
, p. 1903 - 1910 (2008/12/22)
As a continuation of our research and with the aim of obtaining new antimalarial agents, new series of 3-phenylquinoxaline 1,4-di-N-oxide derivatives have been synthesized following the classical Beirut reaction. Antiplasmodial activity was evaluated in v
Synthesis and antimalarial activity of new 3-arylquinoxaline-2-carbonitrile derivatives
Zarranz, Belen,Jaso, Andres,Aldana, Ignacio,Monge, Antonio,Maurel, Severine,Deharo, Eric,Jullian, Valerie,Sauvain, Michel
, p. 754 - 761 (2007/10/03)
New series of 3-arylquinoxaline-carbonitrile derivatives have been synthesized from various 5-substituted or 5,6-disubstituted benzofuroxanes and tested for their in vitro and in vivo activity against the erythrocytic development of Plasmodium falciparum
