877859-93-3

Upstream product

• 26586-36-7 2-(4-(pyrrolidin-1-yl)phenyl)acetic acid 

Downstream Products

• 877859-96-6 3-[2-(4-pyrrolidin-1-yl-phenyl)-acetylamino]-4,6-dihydro-pyrrolo[3,4-c]pyrazole-1-carboxylic acid ethyl ester 
• 877859-95-5 3-[2-(4-pyrrolidin-1-yl-phenyl)-acetylamino]-4,6-dihydro-pyrrolo[3,4-c]pyrazole-1,5-dicarboxylic acid 5-tert-butyl ester 1-ethyl ester 

Relevant academic research and scientific papers

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: A new class of CDK2 inhibitors

We have recently reported about a new class of Aurora-A inhibitors based on a bicyclic tetrahydropyrrolo[3,4-c]pyrazole scaffold. Here we describe the synthesis and early expansion of CDK2/cyclin A-E inhibitors belonging to the same chemical class. Synthe