877861-76-2

Usage

Uses

Used in Pharmaceutical Industry:
1H-Imidazole-2-sulfonyl chloride hydrochloride is used as a coupling agent for the synthesis of peptides, playing a crucial role in the development of various drugs. Its reactivity and solubility make it a valuable component in the creation of new pharmaceutical compounds.
Used in Organic Synthesis:
1H-Imidazole-2-sulfonyl chloride hydrochloride is used as a reagent in the synthesis of organic compounds, particularly in the formation of sulfonyl chlorides and imidazoles. Its versatility in organic synthesis contributes to the development of a wide range of chemical products.
Used in Agrochemical Production:
1H-IMidazole-2-sulfonyl chloride hydrochloride is utilized in the production of agrochemicals due to its versatile properties and potential applications in the agricultural sector. Its ability to form various chemical structures makes it a valuable asset in the development of effective and targeted agrochemicals.
Used in Specialty Chemicals Industry:
1H-Imidazole-2-sulfonyl chloride hydrochloride is also used in the production of specialty chemicals, where its unique properties and reactivity are harnessed to create specialized chemical products for various industries.

Upstream product

• 872-35-5 1,3-dihydro-imidazole-2-thione 

Relevant academic research and scientific papers

COMPOUND CONTAINING BASIC GROUP AND USE THEREOF

The present invention relates to a compound represented by formula (I-0): wherein symbols in formula have the same meanings as described in the present specification, a salt thereof, an N-oxide thereof or a solvate thereof or a prodrug thereof, and medical use thereof The compound of the present invention has an antagonistic activity against CXCR4 and is therefore useful as a preventive and/or therapeutic agent for CXCR4-mediated diseases, for example, inflammatory and immune diseases (for example, rheumatoid arthritis, arthritis, retinopathy, pulmonary fibrosis, transplanted organ rejection, etc.), allergic diseases, infections (for example, human immunodeficiency virus infection, acquired immunodeficiency syndrome, etc.), psychoneurotic diseases, cerebral diseases, cardiovascular disease, metabolic diseases, and cancerous diseases (for example, cancer, cancer metastasis, etc.), or an agent for regeneration therapy.

COMPOUND CONTAINING BASIC GROUP AND USE THEREOF

A compound represented by the general formula (I-0): (I-0) (wherein the symbols are as defined in the description), a salt thereof, N-oxide form thereof, or solvate thereof, or a prodrug of any of these; and a medicinal use of these. The compound has CXCR4 antagonistic activity and is hence useful, e.g., as a preventive and/or therapeutic agent for CXCR4-mediated diseases, e.g., inflammatory/immunologic diseases (e.g., articular rheumatism, arthritis, retinopathy, pulmonary fibrosis, and rejection reactions against transplanted organs), allergic diseases, infectious diseases (e.g., human immunodeficiency virus infection and acquired immunological deficiency syndrome), mental/nervous diseases, brain diseases, cardiac/vascular diseases, metabolic diseases, and carcinomatous diseases (e.g., cancers and cancer metastasis), or as an agent for regenerative medicine.