877866-76-7Relevant academic research and scientific papers
2,5-Disubstituted pyridines: The discovery of a novel series of 5-HT2A ligands
Wilson, Kevin J.,van Niel, Monique B.,Cooper, Laura,Bloomfield, Dawn,O'Connor, Desmond,Fish, L. Rebecca,MacLeod, Angus M.
, p. 2643 - 2648 (2008/02/01)
This report describes the effect of replacing the central basic amine present in many known 5-HT2A ligands with an aromatic residue. We targeted the isomeric phenethylpyridines 2 and 3 and these compounds proved to be excellent leads, possessin
DIARYLSULFONES AS 5-HT2A ANTAGONISTS
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Page/Page column 26, (2008/06/13)
Compounds of formula (I) are potent and selective antagonists of the human 5-HT2A receptor, and hence useful in treatment of a variety of adverse conditions of the CNS.
