877878-47-2 Usage
Uses
Used in Pharmaceutical Research:
[5-(Benzothiazole-2-carbonyl)-2,3,4-trihydroxy-phenyl]-(4-phenoxy-phenyl)-methanone is used as a research compound for exploring its potential biological activities and applications in the development of new drugs. Its complex structure and the presence of various functional groups make it an interesting candidate for further investigation.
Used in Drug Development:
In the pharmaceutical industry, [5-(Benzothiazole-2-carbonyl)-2,3,4-trihydroxy-phenyl]-(4-phenoxy-phenyl)-methanone is used as a lead compound for the design and synthesis of novel therapeutic agents. Its unique structural features may contribute to the development of drugs targeting various diseases and disorders, pending further research and validation.
Used in Chemical Synthesis:
[5-(Benzothiazole-2-carbonyl)-2,3,4-trihydroxy-phenyl]-(4-phenoxy-phenyl)-methanone can also be utilized as a synthetic building block or intermediate in the preparation of other complex organic molecules, particularly those with potential applications in the pharmaceutical, agrochemical, or materials science sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 877878-47-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,7,8,7 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 877878-47:
(8*8)+(7*7)+(6*7)+(5*8)+(4*7)+(3*8)+(2*4)+(1*7)=262
262 % 10 = 2
So 877878-47-2 is a valid CAS Registry Number.
InChI:InChI=1/C27H17NO6S/c29-22(15-10-12-17(13-11-15)34-16-6-2-1-3-7-16)18-14-19(24(31)26(33)23(18)30)25(32)27-28-20-8-4-5-9-21(20)35-27/h1-14,30-31,33H
877878-47-2Relevant academic research and scientific papers
Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins
Tang, Guozhi,Nikolovska-Coleska, Zaneta,Qiu, Su,Yang, Chao-Yie,Guo, Jie,Wang, Shaomeng
, p. 717 - 720 (2008/09/18)
A series of acylpyrogallols were designed, synthesized, and evaluated as small-molecule inhibitors of antiapoptotic Bcl-2 proteins. The most potent compound 9 (TM-179) binds to Bcl-2 with an IC50 of 170 nM and to Mcl-1 with a Ki of 3
SMALL MOLECULE INHIBITORS OF ANTI-APOPTOTIC BCL-2 FAMILY MEMBERS AND THE USES THEREOF
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Page/Page column 49, (2010/10/20)
The invention relates to small molecules which function as inhibitors of anti-apoptotic Bcl-2 family member proteins (e.g., Bcl-2 and Bcl-xL). The invention also relates to the use of these compounds for inducing apoptotic cell death and sensitizing cells to the induction of apoptotic cell death.
