87791-97-7Relevant academic research and scientific papers
Synthesis of 2'-Allyl-2'-Deoxynucleosides by Radical Reactions
Groetli, Morten,Undheim, Kjell
, p. 217 - 224 (2007/10/02)
2'-α-Allyl-2'-deoxynucleosides derived from uridine, cytidine, adenosine and guanosine have been synthesized in high overall yields by photolysis of appropriately protected 2'-O-phenoxythiocarbonyl derivatives in the presence of allyltributylstannane.The 2'-allyl-2'-deoxynucleosides were 5'-O-DMT-protected and converted into 2'-deoxynucleoside 3'-O-phosphoramidites to serve as monomers for oligonucleotides.
