877928-97-7Relevant academic research and scientific papers
Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC
Rose, Yannick,Ciblat, Stephane,Reddy, Ranga,Belley, Adam C.,Dietrich, Evelyne,Lehoux, Dario,McKay, Geoffrey A.,Poirier, Hugo,Far, Adel Rafai,Delorme, Daniel
, p. 891 - 896 (2006)
The preparation and biological evaluation of 5-substituted-6-hydroxy-2- (anilino)pyrimidinones as a new class of DNA polymerase IIIC inhibitors, required for the replication of chromosomal DNA in Gram-positive bacteria, are described. These new dGTP compe
