877994-12-2Relevant academic research and scientific papers
Bicyclic melatonin receptor agonists containing a ring-junction nitrogen: Synthesis, biological evaluation, and molecular modeling of the putative bioactive conformation
Elsner, Jan,Boeckler, Frank,Davidson, Kathryn,Sugden, David,Gmeiner, Peter
, p. 1949 - 1958 (2007/10/03)
Employing 1,3-dipolar cycloaddition for the synthesis of the 7a-azaindole nucleus, analogues of melatonin have been synthesized and tested against human and amphibian melatonin receptors. Introducing a phenyl substituent in position 2 of the heterocyclic
