878011-41-7

Basic information

• Product Name: 3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine
• Synonyms: 3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine;3H-IMidazo[4,5-b]pyridine-3-carboxylic acid, 7-chloro-, 1,1-diMethylethyl ester;tert-butyl 7-chloro-3H-imidazo[4,5-b]pyridine-3-carboxylate
• CAS NO: 878011-41-7
• Molecular Formula: C₁₁H₁₂ClN₃O₂
• Molecular Weight: 253.688
• Mol File: 878011-41-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 357.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3(Predicted)
• PKA: 1.22±0.30(Predicted)
• CAS DataBase Reference: 3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine(878011-41-7)
• EPA Substance Registry System: 3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine(878011-41-7)

Safety Data

• Hazardous Substances Data: 878011-41-7(Hazardous Substances Data)

Usage

General Description

3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine is a synthetic chemical compound with the molecular formula C13H12ClN3O2. It is a derivative of imidazo[4,5-b]pyridine, which has been studied for its potential pharmaceutical applications. The "3-Boc" in its name refers to the tert-butoxycarbonyl (Boc) protecting group attached to the nitrogen atom, while the "7-chloro" indicates the presence of a chlorine atom at the seventh position of the imidazo[4,5-b]pyridine ring. 3-Boc-7-chloro-3H-imidazo[4,5-b]pyridine may have uses in medicinal chemistry, particularly in the development of new drugs targeting specific biological pathways or receptors. Its precise properties and potential applications would need to be investigated further through research and experimentation.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 6980-11-6 7-chloro-3H-imidazo<4,5-b>pyridine 
• 273-21-2 3H-imidazo[4,5-b]pyridine 
• 6863-46-3 Imidazo<4,5-b>pyridine 4-Oxide 

Downstream Products

• 1065479-06-2 N-((8-chloro-2-(2-chlorophenyl)-quinolin-3-yl)methyl)-3H-imidazo[4,5-b]pyridin-7-amine 
• 878011-44-0 2-nitro-6-chloro-9-Boc-1-deazapurine 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND THEIR USES

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also enables methods for treating cancers that are mediated, dependent on, or associated with p110 activity, including but not restricted to leukemias, such as acute myeloid leukaemia (AML), myelo-dysplastic syndrome (MDS), myelo-proliferative diseases (MPD), chronic myeloid leukemia (CML), T-cell acute lymphoblastic leukaemia (T-ALL), B-cell acute lymphoblastic leukaemia (B-ALL), non Hodgkins lymphoma (NHL), B-cell lymphoma and solid tumors, such as breast cancer.