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878051-90-2

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878051-90-2 Usage

Structure

Purine derivative with a purine ring structure

Functional Groups

Chlorine atom ( \textCl )
Methyl group ( \textCH3 )
Nitro group ( \textNO2 )

Applications

Synthesis of pharmaceutical drugs and agrochemicals
Development of antiviral and antitumor agents
Precursor in the synthesis of nucleoside analogs and other pharmaceutical intermediates

Biological Activity

Exhibits potential in antiviral and antitumor activity

Reactivity

Important building block in organic chemistry and drug discovery

Check Digit Verification of cas no

The CAS Registry Mumber 878051-90-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,0,5 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 878051-90:
(8*8)+(7*7)+(6*8)+(5*0)+(4*5)+(3*1)+(2*9)+(1*0)=202
202 % 10 = 2
So 878051-90-2 is a valid CAS Registry Number.

878051-90-2Upstream product

878051-90-2Downstream Products

878051-90-2Relevant articles and documents

Synthetic studies directed towards agelasine analogs - Synthesis, tautomerism, and alkylation of 2-substituted N-methoxy-9-methyl-9H-purin-6- amines

Roggen, Heidi,Gundersen, Lise-Lotte

experimental part, p. 5099 - 5106 (2009/06/06)

N-Methoxy-9-methyl-9H-purin-6-amines, carrying various substituents in the 2 positions, were synthesized by the N-methylation of known 6-chloropurines, followed by a displacement of the chlorine. Great variations in the amino/imino tautomer ratio among the compounds studied were observed. The tautomers were identified by NMR methods. Treatment of N-methoxy-9-methyl-9H-purin-6-amines carrying alkyl, alkoxy, or amino substituents in the 2 position with benzyl bromide resulted in a mixture of N-7- and N6-benzylated compounds with the former as the major products. N-Methoxy-9-methyl-9H-purin-6-amines with strongly electronegative substituents at C-2 hardly reacted at all under the same set of reaction conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

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