878162-31-3 Usage
Molecular structure
1-Pyrrolidinecarboxylic acid, 2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester, (2S)is a complex organic compound consisting of a pyrrolidinecarboxylic acid core, a 2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]group, and a 1,1-dimethylethyl ester group. The (2S)designation indicates the stereochemistry of the compound.
Stereoisomerism
The (2S)designation refers to the specific arrangement of atoms in relation to a chiral center, which means that 1-Pyrrolidinecarboxylic acid,
2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester,
(2S)- is a stereoisomer of other possible isomers with different spatial arrangements.
Applications
1-Pyrrolidinecarboxylic acid,
2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester,
(2S)- may have applications in pharmaceuticals or as a research tool in chemical and biological studies, due to its unique structure and properties.
Safety precautions
It is important to handle and use 1-Pyrrolidinecarboxylic acid,
2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester,
(2S)- with caution, following all safety protocols and regulations, as it may have potential hazards or side effects.
Chemical properties
As an ester, 1-Pyrrolidinecarboxylic acid,
2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester,
(2S)- may undergo hydrolysis, which can break down the ester bond and release the corresponding acid and alcohol. Additionally, the presence of the pyrrolidinecarboxylic acid core and the piperazine ring may contribute to various chemical reactivity and interactions with other molecules.
Physical properties
The specific melting point, boiling point, solubility, and other physical properties of 1-Pyrrolidinecarboxylic acid,
2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester,
(2S)- may be influenced by its molecular structure and stereochemistry, and should be determined through experimental analysis.
Synthesis
The synthesis of 1-Pyrrolidinecarboxylic acid,
2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]-, 1,1-dimethylethyl ester,
(2S)- likely involves multiple steps, including the formation of the pyrrolidinecarboxylic acid core, the attachment of the 2-[[4-(phenylmethyl)-1-piperazinyl]carbonyl]group, and the formation of the 1,1-dimethylethyl ester. The stereochemistry at the chiral center is also crucial and must be controlled during the synthesis process.
Check Digit Verification of cas no
The CAS Registry Mumber 878162-31-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,1,6 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 878162-31:
(8*8)+(7*7)+(6*8)+(5*1)+(4*6)+(3*2)+(2*3)+(1*1)=203
203 % 10 = 3
So 878162-31-3 is a valid CAS Registry Number.
878162-31-3Relevant academic research and scientific papers
Xiao, Jun-An,Liu, Qi,Ren, Ji-Wei,Liu, Jian,Carter, Rich G.,Chen, Xiao-Qing,Yang, Hua
, p. 5700 - 5704 (2014)
The enantioselective 1,3-dipolar cycloaddition of 2-cyclohexene-1-one and azomethine ylides generated in situ from isatins and amino esters was developed by employing prolinosulfonamides as the catalyst. Consequently, novel polycyclic spirooxindole scaffolds with three contiguous stereocenters were prepared in high yield (up to 95%) with excellent diastereo- (>20:1dr) and enantioselectivity (up to 99%ee). The highly enantioselective construction of polycyclic spirooxindoles through 1,3-dipolar cycloaddition of cyclohexenone with azomethine ylides is achieved by employing prolinosulfonamides as the catalyst. This catalytic system essentially benefits from iminium activation and hydrogen-bonding formation induced by the prolinosulfonamides. Copyright
Urea derivatives as calcium channel blockers
-
Page/Page column 14, (2010/10/20)
Urea derivatives which comprise piperidine or piperazine rings and further substitution are effective in ameliorating conditions characterized by unwanted calcium ion channel activity.
