878190-69-3Relevant academic research and scientific papers
General route to dissymmetric heteroannular-functionalized ferrocenyl 1,2-diphosphines: Selective synthesis and characterization of a new class of tri- and tetrasubstituted ferrocenyl compounds
Ivanov,Hierso,Amardeil,Meunier
, p. 989 - 995 (2006)
Several monosubstituted-cyclopentadienyl anions (A-Li) and [1,2-bis(diphenylphosphino)-4-tert-butylcyclopentadienyl]lithium (B-Li) react with FeCl2 to afford a novel class of multidentate ferrocenylphosphines (A-Fe-B). The proposed synthetic method represents a unique means to produce achiral dissymmetric 1,1′,2-substituted ferrocenes (A-Fe-B) bearing a heteroannular 1′-substituent which is different from the homoannular 1- and 2-substituents. The selectivity for the two-step reaction favors formation of the desired dissymmetric product (A-Fe-B) rather than the concurrent formation of the symmetric di- and tetrasubstituted ferrocenes (A-Fe-A and B-Fe-B). Therefore, this method allows access to a great number of dissymmetric multidentate metalloligands, especially when one considers that functionalized-Cp salts continue to expand in terms of number and diversity. Herein, emphasis was placed upon the 1H, 13C, and 31P NMR characterization of the metalloligands; several examples exhibit intriguing conformational properties and rare through-space phosphorus nuclear-spin couplings.
