878194-08-2

Upstream product

• 872989-08-7 (+)-pentafluorophenyl 2-(6-methoxy-naphthalen-2-yl)propionate 
• 86217-38-1 4-phenyl-2-oxazolidinone 
• 1002337-20-3 pentafluorophenyl (+/-)-2-(6-methoxynaphth-2-yl)propionate 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 

Downstream Products

• 960210-90-6 1-phenylethyl 2-(6-methoxynaphthalen-2-yl)propionate 
• 53483-44-6 (R)-2-phenylbutyric acid-(R)-1-phenylethyl ester 
• 79121-13-4 (R)-2-phenylpropionic acid-(R)-1-phenylethyl ester 
• 79121-15-6 (R,S)-Hydratropasaeure-1-phenylester 
• 22204-53-1 (2S)-2-(6-methoxy(2-naphthyl))propanoic acid 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 214492-02-1 (4R)-3-((2S)-2-phenylpropionyl)-4-phenyl-oxazolidin-2-one 

Relevant academic research and scientific papers

Parallel kinetic resolution of racemic oxazolidinones using quasi-enantiomeric active esters

Racemic Evans' oxazolidinones were efficiently resolved using a combination of quasi-enantiomeric profens. The levels of stereocontrol were high, leading to products with predictable configurations.

Efficient parallel resolution of pentafluorophenyl active esters using quasi-enantiomeric combinations of oxazolidin-2-ones

The parallel resolution of racemic pentafluorophenyl 2-aryl/ phenylpropanoates and butanoates using an equimolar combination of quasi-enantiomeric Evans oxazolidin-2-ones is discussed. The levels of diastereoselectivity were excellent (>90% de) leading to separable quasi-enantiomeric oxazolidin-2-ones in good yield. This methodology was used to resolve a series of structurally related 2-aryl/phenylpropanoic and butanoic acids.