878286-14-7Relevant academic research and scientific papers
An Efficient Cyanide-Free Approach towards 1-(2-Pyridyl)isoquinoline-3-carbonitriles via the Reaction of 5-Phenacyl-1,2,4-triazines with 1,2-Dehydrobenzene in the Presence of Alkyl Nitrites
Kopchuk, Dmitry S.,Krinochkin, Alexey P.,Khasanov, Albert F.,Kovalev, Igor S.,Slepukhin, Pavel A.,Starnovskaya, Ekaterina S.,Mukherjee, Anindita,Rahman, Matiur,Zyryanov, Grigory V.,Majee, Adinath,Rusinov, Vladimir L.,Chupakhin, Oleg N.,Santra, Sougata
, p. 483 - 488 (2017/12/06)
A cyanide-free method for the preparation of 1-(2-pyridyl)isoquinoline-3-carbonitriles (3-cyanoisoquinolines) was developed. The interaction of 5-phenacyl-3-(2-pyridyl)-1,2,4-triazines with 1,2-dehydrobenzene generated in situ from anthranilic acid and an
Consecutive nucleophilic substitution and aza Diels-Alder reaction - An efficient strategy to functionalized 2,2′-bipyridines
Kozhevnikov, Dmitry N.,Kozhevnikov, Valery N.,Prokhorov, Anton M.,Ustinova, Maria M.,Rusinov, Vladimir L.,Chupakhin, Oleg N.,Aleksandrov, Grigory G.,K?nig, Burkhard
, p. 869 - 872 (2007/10/03)
An efficient strategy for the synthesis of functionalized 2,2′-bipyridines is reported. The strategy is based on readily available 3-pyridyl-1,2,4-triazine 4-oxides and uses a reaction sequence of nucleophilic substitution of hydrogen and aza Diels-Alder
