878556-89-9Relevant academic research and scientific papers
Synthesis of highly substituted enantiopure piperazines and ketopiperazines from vicinal N-sulfinyl diamines
Viso, Alma,Fernandez De La Pradilla, Roberto,Flores, Aida,Garcia, Ana,Tortosa, Mariola,Lopez-Rodriguez, Maria L.
, p. 1442 - 1448 (2007/10/03)
Enantiopure 1-benzyl-2,3-disubstituted piperazines (4) have been synthesized by treatment of N-sulfinyl-N-benzyldiamino alcohols (1) with diethyl oxalate and sodium methoxide followed by reduction with borane. Alternatively, the sulfinamido group was pres
