878559-99-0

Upstream product

• 65253-04-5 (-)-8-phenylmenthol 
• 1049019-27-3 4-hydroxymethylidene-2-phenyl-4,5-dihydrooxazol-5-one 

Downstream Products

• 878560-00-0 (-)-8-phenylmenthyl (Z)-2-(benzoylamino)-3-(ethoxycarbonyloxy)acrylate 
• 878560-03-3 (-)-8-phenylmenthyl (1R,2R,3S,4S)-2-(benzoylamino)-3-(ethoxycarbonyloxy)bicyclo[2.2.1]heptane-2-carboxylate 
• 878560-01-1 (-)-8-phenylmenthyl 2-(benzoylamino)-3-(ethoxycarbonyloxy)bicyclo[2.2.1]hept-5-ene-2-carboxylate 
• 878560-04-4 (-)-8-phenylmenthyl (1R,2R,3S,4S)-2-(benzoylamino)-3-hydroxybicyclo[2.2.1]heptane-2-carboxylate 
• 878560-08-8 (1S,3R)-3-{(S)-Benzoylamino-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-methyl}-cyclopentanecarboxylic acid methyl ester 
• 878560-05-5 (-)-8-phenylmenthyl (1R,2R,4S)-2-(benzoylamino)-3-oxobicyclo[2.2.1]heptane-2-carboxylate 
• 878560-10-2 (1S,3R,1'S)-3-(1'-(benzoylamino)-1'-carboxymethyl)cyclopentanecarboxylic acid 
• 878560-09-9 (1S,3R,1'R)-3-(1'-(benzoylamino)-1'-carboxymethyl)cyclopentanecarboxylic acid 

Relevant academic research and scientific papers

Enantioselective synthesis of epimeric cis-3-carboxycyclopentylglycines

Two epimeric chiral cyclopentylglycines (-)-16 and (+)-17, functionalised with a carboxy group cis to the amino acid group, were prepared starting from chiral 2-amino-3-oxo-norbornanecarboxylic acid derivative exo-9 by combining two classical reactions such as the Diels-Alder and retro-Claisen reactions. Compounds 16 and 17 are non-proteinogenic amino acids of biological interest containing conformational constraints in which the skeletons of both 2-aminoadipic acid and 2-aminopimelic acid are included.