878662-30-7Relevant academic research and scientific papers
2,5-Disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors
Voelker, Troy,Xia, Haiji,Fandrick, Keith,Johnson, Robert,Janowsky, Aaron,Cashman, John R.
experimental part, p. 2047 - 2068 (2009/06/06)
Enhancement of 5-hydroxytryptamine (5-HT, serotonin) neurotransmission is a viable means of treating depression. On the basis of this observation, agents that inhibit re-uptake of 5-HT were prepared based on (-)-cocaine and aryltropanes as lead compounds
MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS
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Page/Page column 91, (2010/10/20)
Disclosed are agents having pharmacological activity against cellular receptors and intracellular singaling, particularly receptors and sigaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.
Amide derivatives and their therapeutic use
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, (2008/06/13)
A compound of formula (I), wherein R1 and R2 are independently selected from chloro, fluoro, bromo, C1-6 alkyl, C1-6 alkoxy or C1-6 haloalkyl provided that both R1 and R2 are not
