878673-34-8

Upstream product

• 61-58-5 2-deoxy-D-arabino-hexopyranose 
• 391611-29-3 tert-Butyl-[(2R,4aR,6S,8R,8aR)-6-methoxy-2-(4-methoxy-phenyl)-6-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-dimethyl-silane 
• 391611-28-2 tert-Butyl-[(2R,4aR,8R,8aR)-2-(4-methoxy-phenyl)-6-methylene-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-dimethyl-silane 
• 391611-39-5 (2R,4aR,8R,8aR)-8-(tert-Butyl-dimethyl-silanyloxy)-2-(4-methoxy-phenyl)-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-one 
• 391611-27-1 (2R,4aR,8R,8aS)-8-Hydroxy-2-(4-methoxy-phenyl)-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-one 
• 73591-64-7 methyl 1,3-dideoxy-α-D-arabino-heptulopyranoside 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 878673-33-7 (1S,2R,4S,6R,9R)-4-methoxy-9-(4'-methoxyphenyl)-4-methyl-5,8,10-trioxabicyclo[4.4.0]decan-2-ol 

Downstream Products

• 391611-34-0 4-(tert-butyl-diphenyl-silanyloxy)-pent-2-enoic acid (6-{5-[3-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-6-methyl-4-methylene-tetrahydro-pyran-2-yl]-3-methyl-penta-2,4-dienyl}-2,5-dimethyl-tetrahydro-pyran-3-yl)-amide 
• 391611-36-2 spliceostatin A 
• 391611-32-8 (2R,3S,6S)-[6-methoxy-3-(4'-methoxybenzyloxy)-6-methyl-4-methylenetetrahydropyran-2-yl]methyl pivalate 
• 391611-43-1 (2R,3S,6S)-[6-methoxy-3-(4'-methoxybenzyloxy)-6-methyl-4-methylenetetrahydropyran-2-yl]methanol 
• 146478-72-0 FR 901464 
• 391611-31-7 (1S,3R,6R,9S)-8-methoxy-3-(4'-methoxyphenyl)-8-methyl-10-methylene-2,4,7-trioxabicyclo[4.4.0]decane 

Relevant academic research and scientific papers

Total synthesis of FR901464: Second generation

FR901464, a potent cell cycle inhibitor, was synthesized in a convergent manner using natural chiral pool, l-threonine, ethyl (S)-lactate and 2-deoxy-d-glucose as starting materials.

A synthesis of FR901464

FR901464, a potent cell cycle inhibitor, was synthesized in a convergent manner using natural chiral pool, L-threonine, ethyl (S)-lactate and 2-deoxy-D-glucose as starting materials.