878741-78-7

Upstream product

• 77771-02-9 3-bromo-4-fluorobenzaldehyde 
• 165803-94-1 methyl 2-fluoro-5-formylbenzoate 
• 773837-37-9 sodium cyanide 
• 64-17-5 ethanol 
• 709-45-5 2-fluoro-5-bromomethyl benzoic acid methyl ester 
• 816449-70-4 methyl 2-fluoro-5-(hydroxymethyl)benzoate 

Relevant academic research and scientific papers

COMPOUNDS ACTIVE TOWARDS BROMODOMAINS

Disclosed are compounds towards bromodomains, pharmaceutical compositions containing the compounds and use of the compounds in therapy.

PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS

The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula (I): (A chemical formula should be inserted here - please see paper copy enclosed herewith) (I) which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS

The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.