878809-77-9Relevant academic research and scientific papers
PHOSPHOINOSITIDE 3-KINASE INHIBITORS
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Paragraph 0073; 0074; 0075, (2015/03/28)
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R and R6 are each independently (LQ)mY; R4 is H, halogen, optionally substituted aryl or optionally substituted alkyl; and; each X is independently CR7 or N. The compounds are PI3K inhibitors and therefore have potential utility in therapy.
PHOSPHOINOSITIDE 3-KINASE INHIBITORS
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Page/Page column 12, (2013/09/26)
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R and R6 are each independently (LQ) mY; R4 is H, halogen, optionally substituted aryl or optionally substituted alkyl; and; each X is independently CR7 or N. The compounds are PI3K inhibitors and therefore have potential utility in therapy.
HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211
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Page/Page column 306, (2009/10/21)
Chemical Compounds Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
N' - (PHENYL) -N- (MORPHOLIN-4-YL-PYRIDIN-2-YL) -PYRIMIDINE-2, 4-DIAMINE DERIVATIVES AS EPHB4 KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE CONDITIONS
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Page/Page column 57-58, (2008/12/08)
The invention concerns pyrimidine com pounds of Formula (I), or a pharmaceutically acceptable salt thereof where A1, A2, A3, R1, n, R2, R3, and R4 are as defined in the descripti
SUBSTITUTED BIARYL PIPERAZINYL-PYRIDINE ANALOGUES
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Page/Page column 79, (2010/10/20)
Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula (I): wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro,and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
BIARYL PIPERAZINYL-PYRIDINE ANALOGUES
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Page 73, (2008/06/13)
Biaryl piperazinyl -pyri dine analogues are provided, of the Formula (I): wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands, for receptor localization studies.
