ML-098 is a small molecule activator of the GTP-binding protein Rab7, which is involved in the regulation of intracellular trafficking and endosomal transport. It exhibits selectivity against other related GTPases, such as cdc42, Ras, Rab-2A, and Rac1.
878978-76-8
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Basic information
- Product Name: ML-098
- Synonyms: ML-098;ML-809
- CAS NO:878978-76-8
- Molecular Formula: C19H19NO3
- Molecular Weight: 309.35906
- EINECS: N/A
- Product Categories: N/A
- Mol File: 878978-76-8.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 535.5±45.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.17±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.93±0.10(Predicted)
- CAS DataBase Reference: ML-098(CAS DataBase Reference)
- NIST Chemistry Reference: ML-098(878978-76-8)
- EPA Substance Registry System: ML-098(878978-76-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 878978-76-8(Hazardous Substances Data)
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878978-76-8 Usage
Uses
Used in Pharmaceutical Industry:ML-098 is used as a research tool for studying the role of Rab7 in various cellular processes and its potential as a therapeutic target for diseases associated with endosomal dysfunction.
Used in Cancer Research:
ML-098 is used as a potential therapeutic agent for cancer treatment, as it has been shown to induce autophagy and inhibit tumor growth in certain cancer cell lines. Its ability to selectively activate Rab7 may provide a novel approach to targeting cancer cells while minimizing side effects on normal cells.
Used in Neuroscience Research:
ML-098 is used as a research tool to investigate the role of Rab7 in neuronal function and neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Disruption of endosomal trafficking has been implicated in the pathogenesis of these diseases, and ML-098 may help to elucidate the underlying mechanisms and potential therapeutic strategies.
Used in Cell Biology Research:
ML-098 is used as a tool to study the regulation of endosomal transport and intracellular trafficking in various cell types. Understanding the role of Rab7 and its activators, such as ML-098, can provide insights into the molecular mechanisms governing these processes and their implications in various cellular functions and diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 878978-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,9,7 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.Calculate Digit Verification of CAS Registry Number 878978-76:
(8*8)+(7*7)+(6*8)+(5*9)+(4*7)+(3*8)+(2*7)+(1*6)=278
278 % 10 = 8
So 878978-76-8 is a valid CAS Registry Number.
878978-76-8Upstream product
878978-76-8Downstream Products
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ML-098
