879219-77-9Relevant academic research and scientific papers
Acylation of Meldrum's acid with arylacetic acid imidazolides as a convenient method for the synthesis of 4-aryl-3-oxobutanoates
Shimkin,Shirinian,Mailian,Lonshakov,Gorokhov,Krayushkin
experimental part, p. 139 - 142 (2011/09/12)
C-Acylation of Meldrum's acid by (het)arylacetic acids in ethanol in the presence of 1,1′-carbonyldiimidazole leads to ethyl 4-(het)aryl-3- oxobutanoates in high yields.
DNA-protein cross-linking: Model systems for pyrimidine-aromatic amino acid cross-linking
Sun, Guangxing,Fecko, Christopher J.,Nicewonger, Robert B.,Webb, Watt W.,Begley, Tadhg P.
, p. 681 - 683 (2007/10/03)
We have synthesized simple model systems to explore the possibility of photo-cross-linking between the pyrimidine bases and the side chains of the aromatic amino acids. Thymine/phenylalanine and thymine/tyrosine models gave cross-links, and thymine/tryptophan models gave complex mixtures; the cytosine/phenylalanine model was unreactive. The quantum yields for the model cross-linking reactions were 18-46 times smaller than those for thymine dimer formation. Biphotonic excitation contributes little to the yield of these reactions.
