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5-[4-(TrifluoroMethyl)phenyl]-2-piperidone, also known as TFMPP, is a synthetic phenylpiperidine compound that serves as a research chemical. It is recognized for its psychoactive effects, primarily as a serotonin receptor agonist, and has been observed to possess stimulant properties.

87922-74-5

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87922-74-5 Usage

Uses

Used in Research Applications:
TFMPP is utilized as a research chemical for studying the effects of serotonin receptor agonists on the central nervous system. Its psychoactive properties make it a valuable tool in scientific investigations related to mood, behavior, and neurological functions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, TFMPP is used as a lead compound for the development of potential medications targeting serotonin receptors. Its agonistic activity can contribute to the discovery of new treatments for various disorders associated with serotonin dysregulation.
Used in Forensic Toxicology:
TFMPP's classification as a controlled substance and its association with potential health risks make it relevant in forensic toxicology. It is analyzed in cases involving substance abuse or intoxication to determine the presence and effects of 5-[4-(TrifluoroMethyl)phenyl]-2-piperidone.

Check Digit Verification of cas no

The CAS Registry Mumber 87922-74-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,9,2 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 87922-74:
(7*8)+(6*7)+(5*9)+(4*2)+(3*2)+(2*7)+(1*4)=175
175 % 10 = 5
So 87922-74-5 is a valid CAS Registry Number.

87922-74-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(4-(trifluoromethyl)phenyl)piperidin-2-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87922-74-5 SDS

87922-74-5Upstream product

87922-74-5Relevant academic research and scientific papers

Interrupted Pyridine Hydrogenation: Asymmetric Synthesis of δ-Lactams

Wagener, Tobias,Lückemeier, Lukas,Daniliuc, Constantin G.,Glorius, Frank

supporting information, p. 6425 - 6429 (2021/02/22)

Metal-catalyzed hydrogenation is an effective method to transform readily available arenes into saturated motifs, however, current hydrogenation strategies are limited to the formation of C?H and N?H bonds. The stepwise addition of hydrogen yields reactive unsaturated intermediates that are rapidly reduced. In contrast, the interruption of complete hydrogenation by further functionalization of unsaturated intermediates offers great potential for increasing chemical complexity in a single reaction step. Overcoming the tenet of full reduction in arene hydrogenation has been seldom demonstrated. In this work we report the synthesis of sought-after, enantioenriched δ-lactams from oxazolidinone-substituted pyridines and water by an interrupted hydrogenation mechanism.

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